Patent Ductus Arteriosus in Premature Neonates

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Patent ductus arteriosus in premature neonates.

Persistent patency of the ductus arteriosus is a major cause of morbidity and mortality in premature infants. In infants born prior to 28 weeks of gestation, a haemodynamically significant patent ductus arteriosus (PDA) can cause cardiovascular instability, exacerbate respiratory distress syndrome, prolong the need for assisted ventilation and increase the risk of bronchopulmonary dysplasia, in...

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Patent ductus arteriosus in preterm neonates.

Failure of the ductus arteriosus to close within 48-96 hours of postnatal age results in a left to right shunt across the ductus and overloading of the pulmonary circulation. This is more likely to happen in premature neonates with respiratory distress syndrome. Deterioration in the respiratory status on day 3-4 in a ventilated neonate and unexplained metabolic acidosis may be the earliest indi...

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[Preterm neonates with patent ductus arteriosus].

Como citar este artigo: Miyague NI. Persistência do canal arterial em recém-nascidos prematuros. J Pediatr (Rio J). 2005;81:429-30. O canal arterial é um largo vaso que comunica a artéria pulmonar com a aorta no feto. É uma estrutura de grande importância nesse período da vida, pois uma maior porção do débito ventricular combinado passa através dessa comunicação à aorta descendente e à placenta...

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Intravenous Paracetamol and Patent Ductus Arteriosus Closure

Background: Standard medical treatments for patent ductus arteriosus (PDA) closure are, including indomethacin/ibuprofen and surgical ligation. Nowadays, a new strategy to close PDA is the use of paracetamol. The present study aimed to describe the use of intravenous (IV) paracetamol for PDA closure in neonates who present a contraindication to ibuprofen or ibuprofen failure with no possibility...

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Ligation of patent ductus arteriosus in very low birthweight premature neonates.

The results of ligation of a patent ductus arteriosus in 30 premature neonates with a very low birth weight were analysed. The mean gestational age at birth was 27 weeks and the mean weight 811 g. Attempted closure of the ductus with indomethacin in 19 infants failed, though there was temporary closure in nine. Congestive heart failure was present in 29 and respiratory distress in 22 patients. ...

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ژورنال

عنوان ژورنال: Drugs

سال: 2012

ISSN: 0012-6667

DOI: 10.2165/11632870-000000000-00000